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Search Results to Meenakshisundaram Balasubraman

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Balasubramaniam, Meenakshisundaram

One or more keywords matched the following items that are connected to Balasubramaniam, Meenakshisundaram

Item Type	Name
Concept	Protein Conformation
Concept	Protein Binding
Concept	Protein Transport
Concept	Ubiquitin-Protein Ligases
Concept	Protein Multimerization
Concept	Protein Folding
Concept	Protein Unfolding
Concept	Protein Structure, Secondary
Concept	Protein Kinase Inhibitors
Academic Article	Proteins in aggregates functionally impact multiple neurodegenerative disease models by forming proteasome-blocking complexes.
Academic Article	Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls.
Academic Article	PIP3-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans.
Academic Article	Biological evaluation of 2-arylidene-4, 7-dimethyl indan-1-one (FXY-1): a novel Akt inhibitor with potent activity in lung cancer.
Academic Article	Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegans.
Academic Article	Aspirin-Mediated Acetylation Protects Against Multiple Neurodegenerative Pathologies by Impeding Protein Aggregation.
Academic Article	Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs.
Academic Article	ALS-causing mutations in profilin-1 alter its conformational dynamics: A computational approach to explain propensity for aggregation.
Academic Article	Structural insights into pro-aggregation effects of C. elegans CRAM-1 and its human ortholog SERF2.
Grant	Early Events in Alzheimer Pathogenesis
Academic Article	Aggregate Interactome Based on Protein Cross-linking Interfaces Predicts Drug Targets to Limit Aggregation in Neurodegenerative Diseases.
Academic Article	Interleukin-1? drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site.
Academic Article	Structural Characterization of the Aurora Kinase B "DFG-flip" Using Metadynamics.
Academic Article	A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer's Disease.
Academic Article	FCX-146, a potent allosteric inhibitor of Akt kinase in cancer cells: Lead optimization of the second-generation arylidene indanone scaffold.
Academic Article	Structural modeling of GSK3? implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs.
Academic Article	"Protein aggregates" contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation.
Academic Article	Antitumor properties of novel sesquiterpene lactone analogs as NF?B inhibitors that bind to the IKK? ubiquitin-like domain (ULD).
Academic Article	Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease.
Academic Article	Glial Fibrillary Acidic Protein: A Biomarker and Drug Target for Alzheimer's Disease.
Academic Article	In silico analysis of TUBA4A mutations in Amyotrophic Lateral Sclerosis to define mechanisms of microtubule disintegration.
Academic Article	Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain.
Grant	Neuroinflammation, Protein Aggregates, ApoE4 Drug Targeting, and Autophagy Rescue
Grant	Neuroinflammation, Protein Aggregates, ApoE4 Drug Targeting, and Autophagy Rescue
Academic Article	Epidermal Growth Factor Receptor Inhibitors in Glioblastoma: Current Status and Future Possibilities.
Grant	Neuroinflammation, Protein Aggregates, ApoE4 Drug Targeting, and Autophagy Rescue

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